My story
The best PCOS supplements in 2025
I spent months researching PCOS supplements comparing ingredients, reading clinical studies, and testing some myself.
Not because I had to, but because I needed to
.If you're tired of “miracle fixes” and don't know who to trust anymore, this guide is for you.
These are the top 5 formulas I’d actually recommend to a friend ❤.
Show me the top 5
Why did I start this
review ?
I was diagnosed with PCOS at 24 — after years of:
- Irregular or missing periods
- Persistent acne, even in adulthood
- Sudden weight gain, despite no major lifestyle changes
- Fatigue I couldn’t explain
- Facial hair growth that made me feel self-conscious
Like so many women, I was told it was “just stress” or “part of being a woman.” I left the doctor’s office with more confusion than clarity and no clear path forward.
So I started digging. I read research papers, decoded supplement labels, and tested products on myself. Some helped, some didn’t. But I learned to tell the difference between marketing fluff and actual, evidence-backed support.
That’s why I created this guide — to help other women like me find real, trustworthy solutions in the middle of the hormonal health maze.
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Why it matters
Why does this research matter ?
Up to 70% of women with PCOS remain undiagnosed.
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
PCOS isn't just a fertility condition
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
Supplements take time
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
Many popular PCOS supplements are poorly formulated
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
My review note
9.2 / 10
7.5 / 10
7.9 / 10
7.4 / 10
6.9 / 10
Dual-action Inositol (40:1)
Methylated Folate
Adaptogens (Rhodiola, Maca)
Made in Europe
No synthetic fillers
Brand transparency
Community support
Quick comparaison
My top picks at a glance
Looking for the best PCOS support supplements? Here’s a quick look at my top 5 favorites: tested, rated, and trusted.
See the full comparaison
Small diagnosis
What is PCOS exactly ?
Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder that affects women of reproductive age. It’s marked by hormonal imbalances, irregular periods, and sometimes, small fluid-filled sacs (follicles) in the ovaries. Despite the name, you don’t need cysts to have PCOS.
How to identify PCOS ?
What are the most common symptoms ?
What causes PCOS ?
Is PCOS only about fertility ?
Do I need a scan or blood test to know if I have it ?
How to identify PCOS ?
Irregular cycles
Missing periods ? Long cycles ? Spotting randomly ?
Fatigue & energy crashes
Constantly tired especially after eating?
Hormonal skin & hair changes
Struggling with acne, oily skin, or unexpected hair growth or thinning?
Weight gain around the belly
Stubborn belly fat or bloating, even without changing your habits?
Mood swings or anxiety
Feeling emotionally up and down, without a clear reason?
Cravings & blood sugar crashes
Intense cravings for sugar or carbs?
Even if you haven’t received a formal diagnosis, these symptoms may point to a hormonal imbalance. I always recommend seeking medical advice — but also, trust yourself. You know your body better than anyone.
Nutrition tips
Why targeted nutrition is key to managing hormonal imbalances
There’s no magic cure for PCOS but the right nutrients, taken consistently, can gently support your hormones, improve insulin response, balance your energy and mood, and help bring more regularity to your cycle.
Myo + D-Chiro Inositol
Improves insulin sensitivity, promotes ovulation, and reduces androgen levels.
Insulin regulation
Zinc + Vitamin B6
Supports progesterone, reduces testosterone, improves mood and skin.
Hormonal balance
Berberine
A natural insulin sensitizer, shown to support metabolic health as effectively as metformin in some studies.
Insulin Regulation + Metabolic support
Methylated Folate
Essential for hormone production, egg quality, and reproductive health — even if you're not trying to conceive.
Hormonal Balance + Reproductive Health
Framework review
Why targeted nutrition is key to managing hormonal imbalances
With so many options claiming to be 'the best,' choosing a supplement can feel overwhelming. I developed a review process grounded in research, ingredient quality, and real user experience — not just brand promises.
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My method
Our promise: A rigorous selection process, step by step
Every product we recommend goes through a thoughtful and transparent review journey — here’s how we do it.
Evidence-based ingredients
We start with science. Every formula we look at includes ingredients backed by real clinical research. No empty claims.
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Effective dosages
It's not just what’s in the supplement — it’s how much. We verify that dosages match what’s shown to work in studies.
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Clean formulation
We exclude any product with synthetic fillers, harmful additives, or anything we wouldn’t take ourselves.
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Holistic benefits
We look beyond symptoms: we aim for whole-body support — energy, mood, hormone balance, metabolism, and more.
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Brand transparency
We only trust brands that share what’s inside, how it’s sourced, and are open about their processes and values.
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Real feedback from real women
We only trust brands that share what’s inside, how it’s sourced, and are open about their processes and values.
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Scientific references & Clinical research
All supplement evaluations on this site are grounded in existing clinical research and peer-reviewed studies. Below are some of the key publications that informed my approach:
Mishra N, Verma R, Jadaun P. Study on the Effect of Berberine, Myoinositol, and Metformin in Women with Polycystic Ovary Syndrome: A Prospective Randomised Study. Cureus. 2022 Jan 31;14(1):e21781. doi: 10.7759/cureus.21781. PMID: 35251851; PMCID: PMC8890747.Study on the Effect of Berberine, Myoinositol, and Metformin in Women with Polycystic Ovary Syndrome: A Prospective Randomised
Study
Lete, Iñaki, Ainara Martínez, Irene Lasaga, Eva Centurión, and Amaia Vesga. 2024. “Update on the Combination of Myo-Inositol/d-Chiro-Inositol for the Treatment of Polycystic Ovary Syndrome.” Gynecological Endocrinology 40 (1). doi:10.1080/09513590.2023.2301554.
Greff, D., Juhász, A. E., Váncsa, S., Váradi, A., Sipos, Z., Szinte, J., Park, S., Hegyi, P., Nyirády, P., Ács, N., Várbíró, S., & Horváth, E. M. (2023). Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reproductive biology and endocrinology : RB&E, 21(1), 10. https://doi.org/10.1186/s12958-023-01055-z
Reznichenko, H., & Reznichenko, Y. (2021). Inositol and folates in the restoration of reproductive function in women and prevention of congenital malformations: Literature review . REPRODUCTIVE ENDOCRINOLOGY, (61), 95–100. https://doi.org/10.18370/2309-4117.2021.61.95-100
ElObeid, T., Awad, M. O., Ganji, V., & Moawad, J. (2022). The Impact of Mineral Supplementation on Polycystic Ovarian Syndrome. Metabolites, 12(4), 338. https://doi.org/10.3390/metabo12040338
Rose DP. The interactions between vitamin B6 and hormones. Vitam Horm. 1978;36:53-99. doi: 10.1016/s0083-6729(08)60982-6. PMID: 217175.
Avoid
What to avoid when choosing a PCOS supplement
(Avoid making the same mistakes as I did)
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Hidden formulas & low doses
Many products hide behind vague ingredient lists or "proprietary blends" meaning you never really know how much you're getting.
Always look for transparency and clinically relevant doses.
Cheap fillers over quality
Supplements packed with synthetic folic acid, artificial sweeteners or magnesium stearate might look affordable. But your body deserves better.
Opt for clean, bioavailable ingredients your body can actually use.
Brands with no face
If you can’t find out who’s behind the brand, how to contact them, or what they stand for, it’s a red flag.
You deserve support, not just a supplement.
Miracle claims
Be wary of brands that promise results in just a few days, supplements aren’t magic pills.
Hormonal balance takes time, consistency, and science.
Amazon-only brands
Some sellers on third-party marketplaces cut corners: fake reviews, poor quality, no guarantees.
Trust brands with real websites, real contact info, and real values.
Too-good-to-be-true reviews
If every review says “worked instantly” or sounds copy-pasted, take a pause.
Real results take time, and real people have nuance. Look for honest, detailed feedback — not hype.
My top 5
The top 5 best PCOS supplements in 2025 (in my opinion)
What makes Ovastart different
In a space filled with overpromising supplements and “miracle cycles in 3 days”, Ovastart® does the opposite. It focuses on what works, and nothing else.
By SOVA (visit website)
Pros :
- Dual-action inositol: Myo + D-Chiro in optimal ratio
- Methylated folate (Quatrefolic®): No synthetic folic acid here
- Bioavailable forms of Zinc & B6: Easier on digestion, more effective
- Formulated in France under strict quality controls — not a white-label copy
- No fillers, no fluff: Just active ingredients your body can use
- Created by women who live with PCOS: Real experience behind the product
- 3-month packs available: Cost-saving and gives your body time to respond
- 10% Reduction with code “LABELS10” on your first order (above £60)
Cons :
- Still relatively new in the UK market — but growing
- Online-only: Not available in stores (yet)
- No subscription plan (yet) for auto-refill ease
- Higher price point than generic options — but you get what you pay for (and 10% off your first order above £60 thanks to my code LABELS10)
Start your routine
Ovastart by Sova
Premium hormonal support for women with PCOS.
What makes it different :
Myo & D-Chiro Inositol
Methylated folate (Quatrefolic®)
Bioavailable Zinc, B6, B12, Chromium
Vegan formulation
100% clean, no synthetic fillers
Made in France – GMP certified
Why did I choose Sova ?
I wasn’t sure where to start, their product quiz helped me figure it out. PCOS is so complex, and SOVA’s quiz made it easy to find what actually fit my symptoms.
They don’t just sell, they educate. From Instagram reels to deep-dive articles, SOVA helps me understand my hormones instead of just masking symptoms.
I felt seen, not sold to. It didn’t feel like a brand trying to push a quick fix, it felt like a community (+50K women) that gets what I’m going through.
The formula actually evolves with the science. Ovastart uses patented ingredients (like Quatrefolic®) and updates its formulas based on the latest research — not trends.
Start your routine
QSTA Inositol Powder
In a market full of marketing promises, QSTA’s Inositol Powder is a decent entry-level pick. It offers the basics — myo- and d-chiro-inositol, some vitamins, and vegan ingredients — without going overboard. If you’re just starting your journey with PCOS supplements and looking for something simple and accessible, this could be a good place to start.
But it’s not built for the long run. The formula lacks depth, omitting key nutrients like zinc and B6. It uses synthetic folic acid instead of methylated folate (less bioavailable), and the low doses of magnesium or D3 may not make a meaningful impact. Still, it’s affordable and widely available.
Pros :
- Combines myo-inositol + d-chiro-inositol
- Includes vitamin D3, magnesium, and folic acid
- Vegan-friendly
- Affordable and widely available
Cons :
- Uses synthetic folic acid instead of methylfolate (less bioavailable)
- Low doses of magnesium and D3 — not enough for noticeable results
- Missing key nutrients like zinc, B6, or chromium for full hormonal/metabolic support
- Formula mainly targets fertility, not broader PCOS symptoms
- Limited transparency on sourcing and testing
- Some users report mild bloating or nausea, especially on an empty stomach
- Not ideal for long-term support — more of a starter option
Product info
Myo & D-Chiro Inositol complex by Oxford Origins
A clean, minimalist pick — but limited in scope.Oxford Origins keeps things simple: Myo & D-Chiro Inositol in capsule form, with no sweeteners, fillers, or unnecessary extras. Made in the UK, it's a reassuringly clean option if you're just looking for basic hormonal support.
But that minimalist approach comes with trade-offs. There’s no support for fatigue, skin, mood, or inflammation — and no extra nutrients like zinc or B-vitamins to round things out. It does one job well, but it’s not a full-spectrum solution.
Pros :
- Simple formula with 2000mg Myo-Inositol + 50mg D-Chiro-Inositol
- Clean capsule format — no sweeteners, flavours, or fillers
- Easy to swallow
- Made in the UK
Cons :
- Missing key co-factors like zinc, B6, folate, or chromium
- No adaptogens or ingredients for mood, fatigue, or skin
- Only one active mechanism: inositol (no multi-angle support)
- Not tailored to metabolic or inflammatory PCOS symptoms
- No official site, Amazon only
- Limited background on the brand or clinical testing
- Slightly higher price point for a very basic blend
Product info
Della – Inositol Complex
Della’s formula looks good on paper: it combines Myo-Inositol with key nutrients like chromium and magnesium, in a clean, modern-looking package. At first glance, it seems like a reliable mid-range pick for anyone starting PCOS support.
But once you look closer, it gets blurry: no official website, no expert endorsements, and no real visibility on where the product comes from. It's available on Amazon, but beyond that, there’s not much reassurance. Good for testing the waters — but probably not your long-term go-to.
Pros :
- Contains 4000mg of Myo-Inositol, the science-backed dose recommended for PCOS
- Includes Chromium and Magnesium
- Vegan-friendly and free from artificial fillers or binders
- Packaging is clean and informative
Cons :
- Uses synthetic folic acid, not methylated folate (less bioavailable)
- No clinical backing, no visible experts, or trust signals
- Unclear ownership — possibly part of a UAE-based group with no public-facing team
- Customer service difficult to access beyond Amazon
- No bundle discounts or subscription options to reduce cost
- Amazon-only presence, with limited third-party reviews or feedback
Product info
Bettervits – PCOS Complex
Looks strong on paper — less so in practice.
Bettervits’ PCOS Complex includes an impressive mix of ingredients — from Myo-Inositol and Folic Acid to Maca Root and Berberine, in high dosages. On paper, it looks like a powerful combo that checks all the boxes.
But in real life ? The experience can fall short.
The tablets are big, bitter, and hard to take consistently (especially four times a day). Some users feel quick effects, while others struggle to notice anything meaningful. The lack of transparency — and limited customer support — makes it harder to trust in the long term.
Pros :
- Includes a broad spectrum of key ingredients: Myo-Inositol, Maca Root, Berberine, Folic Acid
- High dosages: 4000mg Myo-Inositol, 10,000mg Maca Root — among the most concentrated on the market
- Made in the UK
Cons :
- Format is tablets, not capsules (less common and often harder to digest)
- Very large tablets — difficult to swallow even when split
- Bitter taste makes regular use unpleasant
- Berberine may trigger hypoglycemia if you don’t have insulin resistance
- Some questions raised in reviews about actual ingredient ratios
- No clear breakdown of vitamin co-factors or formulation science
- Hard to get in touch with Bettervits customer support for questions or advice
- Some reviews claim it “worked in days” — which can feel unrealistic
- Slightly higher price point for a very basic blend
Product info
Why I chose Ovastart as my
#1 pick
After years of trial and error with PCOS supplements, Ovastart was the first one that felt like it truly understood what I needed. Clean ingredients, no fluff, and real results. My cycles got more regular, and I finally felt like myself again
